8-10/2010
Source: Cedars-Sinai Medical Center
In the journal of the American College of cardiology: cardiovascular Imaging, Cedars-Sinai Medical Center researchers say fat around the heart is more predictive than around the waist
LOS ANGELES (6 October 2010) heart imaging researchers in the Cedars-Sinai Heart Institute recommend that doctors are not fat deposits around the heart forget in the evaluation of patients at risk of major heart problems.
Although abdominal fat is often considered to be in making these assessments, recent research suggests that the measurement of adipose tissue around the heart an even better Predictor and noninvasive CT scan can offer this important information.
The recommendation appeared in an editorial published in the journal of the American College of cardiology: cardiovascular Imaging. Daniel s. Berman, MD, head of the cardiac imaging in the Cedars-Sinai Heart Institute and Cedars-Sinai s. Mark Taper Foundation Imaging Center, is the first author of the article and a leading authority in the heart imaging.
The published opinion was requested by another article in the magazine in which researchers demonstrate new abdominal fat must be linked to the instability of coronary arterial plaques.In the current theory, people with higher risk of excess abdominal fat accumulation of plaque and heart disease and plaque to rupture a greater threat than those which are stable.
With the co-authors Victor y. Cheng, M.D., and Damini Dey, Ph. d., Berman cites several studies that fat around the heart and the coronary arteries to inflammation and plaque development linking and suggests that fat around the heart and the coronary arteries "may be more potent determinants of coronary plaque development and progress than visceral abdominal fat."This fat around the heart is also involved in the development of important heart side effects (MACE), defined as heart-related death, fatal heart attack, surgery to get around Blocked heart arteries or repeated percutaneous coronary intervention (angioplasty) to reopen blocked arteries.
Under the leadership of Berman recently Cedars-Sinai the largest randomized trial of coronary artery calcium CT scan, after 2,137 subjects over four years.More than 20,000 patients are now entered in a register of the persistent data. this technology gives plaque deposits in the arteries by detecting of calcium, a powerful component of the plaque.In addition, using the methods of the software, can coronary artery calcium CT scan also be used to fat around the heart and the coronary arteries. The two measurements taken together plate and increased fat around the heart appear to improve the quality of life in the prediction of patients there is a risk of major heart problems.
In their study of the coronary artery calcium CT scan the researchers found Cedars-Sinai and other sites that patients are not affected by any signs of heart disease but had a significant adverse cardiac event experienced had more heart than fat around the issues that had no events. when they are a measure of FAT volume around the heart with conventional risk factors and coronary calcium scan, they were better able to predict what patients are more likely to great heart problems. in another study the researchers found that the amount of fat around the heart is strongly associated with the narrowing of the coronary arteries caused by plaque.
"Meet pericardial fluid fat from the heart CT primer seems to end up with a routine addition to the information that is gained from the evaluation of the plaque," the researchers conclude. "This assessment can generate CT information with regard to the business of atherosclerotic process (construction of plaque) add to meaningful clinical evaluation. "
The work was partially supported by grants from the Eisner Foundation, the Foundation Glazer, the Lincy Foundation, and the National Institute of Biomedical Imaging and bioengineering (National Institute of Health). Berman receives support research by Siemens Medical Systems.
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